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This mechanism is incredibly relevant for patients with Long COVID and ME/CFS, as these specific cytokines are the primary drivers of the systemic inflammation that sustains their symptoms

147 Imipramine acts as an antidepressant by increasing the mRNA expression of BDNF in astrocytes

Pentose Sugar Metabolism: The HMP shunt provides pentose sugars that serve as precursors for nucleotides and play roles in other cellular processes, such as amino acid metabolism